BPGM anticorps (C-Term)
Aperçu rapide pour BPGM anticorps (C-Term) (ABIN950665)
Antigène
Voir toutes BPGM AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 229-259, C-Term
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Specificité
- This antibody reacts to Bisphosphoglycerate mutase.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 229-259 amino acids from the C-terminal region of human BPGM
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) sodium azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BPGM (2,3-bisphosphoglycerate Mutase (BPGM))
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Autre désignation
- Bisphosphoglycerate Mutase
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Sujet
- 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.Synonyms: 2, 3-bisphosphoglycerate mutase, 3-bisphosphoglycerate synthase, BPG-dependent PGAM, BPGM, erythrocyte
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ID gène
- 669
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NCBI Accession
- NP_001715
Antigène
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