BPNT1 anticorps (C-Term)

N° du produit ABIN950676

Détail du produit anti-BPNT1 anticorps

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Épitope: AA 276-305, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BPNT1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to BPNT1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 276-305 amino acids from the C-terminal region of human BPNT1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur BPNT1

Antigène: BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))

Autre désignation: BPNT1 (BPNT1 Produits)

Synonymes: anticorps BPNT1, anticorps PIP, anticorps Sal3, anticorps BPntase, anticorps 3'(2'), 5'-bisphosphate nucleotidase 1, anticorps bisphosphate 3'-nucleotidase 1, anticorps BPNT1, anticorps bpnt1.L, anticorps Bpnt1

Sujet: BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.Synonyms: 3'(2'), 4-phosphatase, 5'-bisphosphate nucleotidase 1, Bisphosphate 3'-nucleotidase 1, PAP-inositol-1

ID gène: 10380

NCBI Accession: NP_006076

Pathways: Inositol Metabolic Process