Calpain 6 anticorps (Middle Region)

N° du produit ABIN951010

Cet anticorps Lapin Polyclonal détecte spécifiquement Calpain 6 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour Calpain 6 anticorps (Middle Region) (ABIN951010)

Antigène: Calpain 6 (CAPN6)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Calpain 6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Calpain 6 anticorps

Épitope: AA 289-319, Middle Region

Specificité: This antibody reacts to CAPN6.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 289-319 amino acids from the Central region of human CAPN6

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Calpain 6

Antigène: Calpain 6 (CAPN6)

Autre désignation: Calpain-6

Sujet: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis.Synonyms: CALPM, CANPX, CAPN6, Calpain-like protease X-linked, Calpamodulin

Poids moléculaire: 74576 Da

ID gène: 827

NCBI Accession: NP_055104