CARM1 anticorps (Middle Region)
Aperçu rapide pour CARM1 anticorps (Middle Region) (ABIN951046)
Antigène
Voir toutes CARM1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Specificité
- This antibody reacts to PRMT4.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide selected from the Central region of human PRMT4
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CARM1 (Coactivator-Associated Arginine Methyltransferase 1 (CARM1))
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Autre désignation
- CARM1 / PRMT4
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Sujet
- Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).Synonyms: Coactivator-associated arginine methyltransferase 1, Histone-arginine methyltransferase CARM1, Protein arginine N-methyltransferase 4
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Poids moléculaire
- 65854 Da
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ID gène
- 10498
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NCBI Accession
- NP_954592
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of fat Cell Differentiation
Antigène
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