Cathepsin K anticorps (Middle Region)

N° du produit ABIN951065

L’anticorps anti-Cathepsin K Polyclonal Lapin est utilisé pour la détection de Cathepsin K dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour Cathepsin K anticorps (Middle Region) (ABIN951065)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Cathepsin K anticorps

Épitope: AA 96-126, Middle Region

Specificité: This antibody recognizes Human Cathepsin K.

Réactivité croisée (Details): Species reactivity (expected):Bovine, MonkeySpecies reactivity (tested):Human

Purification: Saturated Ammonium Sulfate (SAS) Precipitation

Immunogène: KLH conjugated synthetic peptide between 96-126 amino acids from the Central region of Human Cathepsin K Genename: CTSK

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: Cathepsin K

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq].Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Poids moléculaire: 36966 Da

ID gène: 1513

NCBI Accession: NP_000387

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades