Endoglin anticorps (Middle Region)
Aperçu rapide pour Endoglin anticorps (Middle Region) (ABIN951149)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 272-302, Middle Region
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Specificité
- This antibody recognizes Human CD105 / Endoglin (Center).
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 272-302 amino acids from the Central region of Human CD105 / Endoglin. Genename: ENG
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Endoglin (ENG)
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Autre désignation
- CD105 / Endoglin
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Sujet
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: END, ENG, HHT1, ORW, ORW1
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Poids moléculaire
- 70578 Da
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ID gène
- 2022
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NCBI Accession
- NP_000109
Antigène
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