L1CAM anticorps (C-Term)

N° du produit ABIN951209

L’anticorps anti-L1CAM Polyclonal Lapin est utilisé pour la détection de L1CAM dans des échantillons de Humain et Souris. Il a été validé pour WB et EIA.

Aperçu rapide pour L1CAM anticorps (C-Term) (ABIN951209)

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp L1CAM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-L1CAM anticorps

Épitope: AA 1153-1182, C-Term

Specificité: This antibody detects CD171 / L1CAM at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse

Purification: Purified through a protein A column, followed by peptide affinity purification.

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 1153-1182aa) of human CD171 / L1CAM.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur L1CAM

Antigène: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Autre désignation: CD171 / L1CAM

Sujet: L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.Synonyms: CAML1, MIC5, N-CAM L1, Neural cell adhesion molecule L1

ID gène: 3897

NCBI Accession: NP_000416

Pathways: Synaptic Membrane