CD1e anticorps (Middle Region)
Aperçu rapide pour CD1e anticorps (Middle Region) (ABIN951216)
Antigène
Voir toutes CD1e AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 274-304, Middle Region
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Specificité
- This antibody reacts to CD1E.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 274-304 amino acids from the Central region of human CD1E
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Isotype
- Ig Fraction
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Indications d'application
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ELISA: 1/1000. Western blot: 1/100 - 1/500. Immunohistochemistry on paraffin sections: 1/50 - 1/100. Flow Cytometry: 1/10 - 1/50. Immunofluorescence: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD1e
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Autre désignation
- CD1E
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Sujet
- CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.Synonyms: CD_antigen=CD1e, R2G1, T-cell surface glycoprotein CD1e, hCD1e, membrane-associated, sCD1e, soluble
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Poids moléculaire
- 43626 Da
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ID gène
- 913
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NCBI Accession
- NP_001036048
Antigène
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