CD226 anticorps (FITC)

N° du produit ABIN951229

Cet anticorps Rat Monoclonal détecte spécifiquement CD226 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD226 anticorps (FITC) (ABIN951229)

Antigène: CD226

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD226 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 15F-10E5

Détail du produit anti-CD226 anticorps (FITC)

Specificité: Recent experiments show that this antibody (clone 15F.10E5) only binds to differentiated Th1 cells but not Th2 or Th0 cells. It also suppressed both antigen-specific T cell expansion and an autoimmune disease (EAE) mediated by effector Th1 cells.

Immunogène: AE7 cells Donor: Lewis rat Fusion Partner: SP 2/0 myeloma

Isotype: IgM

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD226

Antigène: CD226

Autre désignation: CD226 / DNAM1

Sujet: CD226 (also called DNAM-1) is constituitively expressed on naive CD8+ T cells, as well as subsets of naive CD11b+ macrophages and NK cells. It is also found on a lower percentage (~40 % ) of unactivated CD4+ T cells. CD226 is functional upon T cell activation, and CD226 ligands (CD112 and CD155) are the same in the mouse as for human (Tage-4 is the mouse homologue of CD155). The gene for mouse DNAM-1 was identified on chromosome 18, and the predicted amino acid sequence shows a 53 % homology with human DNAM-1.Synonyms: DNAM-1, DNAX accessory molecule 1

ID gène: 225825

NCBI Accession: NP_848802

UniProt: Q8K4F0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints