CD235a/GYPA anticorps

N° du produit ABIN951236

L’anticorps Lapin Polyclonal anti-CD235a/GYPA a été validé pour FACS, WB et EIA. Il convient pour détecter CD235a/GYPA dans des échantillons de Humain.

Aperçu rapide pour CD235a/GYPA anticorps (ABIN951236)

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD235a/GYPA est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-CD235a/GYPA anticorps

Specificité: Anti-human Glycophorin A (GpA) Polyclonal Antibody targets the human Glycophorin A protein. This polyclonal antibody recognizes various epitopes on the GpA protein. The 23 residue hydrophobic transmembrane domain has been shown to mediate non-covalent dimerization of the protein under conditions of SDS page (and in other detergents). We also sell a FITC conjugated version of this antibody (AP31671FC-N).

Purification: Affinity chromatography on Protein G

Immunogène: Human Glycophorin A transmembrane protein Donor: Rabbit serum

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD235a/GYPA

Antigène: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Autre désignation: CD235a / GYPA

Sujet: This 131 amino acid, 36 KDa, transmembrane sialoglycoprotein spans the membrane of erythrocytes once. GpA presents its N terminus at the extracellular surface of the human red blood cell, has a single transmembrane domain and an internal cytoplasmic C terminus. GpA contributes to the expression of blood group antigen M and N specificities, which work to prevent red blood cell aggregation in circulation. Studies show that GpA is expressed early on the cell surface during erythropoiesis as pluripotent stem cells are recruited to differentiate into erythrocytes. This makes GpA a useful marker for studying the developmental biology of hematopoietic progenitor cells.Synonyms: GPA, Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha

ID gène: 2993

NCBI Accession: NP_002090

Pathways: Maintenance of Protein Location