CD5 anticorps (PE)

N° du produit ABIN951345

Cet anticorps anti-CD5 est un anticorps Rat Monoclonal détectant CD5 dans FACS. Adapté pour Humain et Souris.

Aperçu rapide pour CD5 anticorps (PE) (ABIN951345)

Antigène: CD5

Reactivité: Humain, Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD5 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 03-07-53

Détail du produit anti-CD5 anticorps (PE)

Specificité: This CD5 (Ly-1) Monoclonal Antibody is specific for the Mouse CD5 antigen.

Purification: Protein G Chromatography

Immunogène: Mouse thymus or spleen from Balb/c mouse thymus or spleen.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CD5

Antigène: CD5

Autre désignation: CD5

Sujet: CD5 is a 55 kDa T lymphocyte single chain transmembrane glycoprotein. It is present on all mature T lymphocytes, on most thymocytes and on many T cell leukemias and lymphomas. It reacts with a subpopulation of activated B cells. CD5/Lyt1 antigen is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B cell antigen CD72. The frequency of CD5+ B cells exhibits strain dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B1 cells. Binding of CD5 on the T cell surface can augment alloantigen or mitogen induced lymphocyte proliferation and induces increased cytosolic free calcium, IL2 secretion, and IL2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T cell and B cell receptors.Synonyms: CD5, LEU1, Lymphocyte antigen T1/Leu-1, T-cell surface glycoprotein CD5

ID gène: 12507

NCBI Accession: NP_031676

UniProt: P13379