ACTR1A anticorps (Middle Region)

N° du produit ABIN951473

L’anticorps Lapin Polyclonal anti-ACTR1A a été validé pour WB et EIA. Il convient pour détecter ACTR1A dans des échantillons de Humain et Souris.

Aperçu rapide pour ACTR1A anticorps (Middle Region) (ABIN951473)

Antigène: ACTR1A (Alpha Centractin (ACTR1A))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTR1A est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-ACTR1A anticorps

Épitope: AA 97-126, Middle Region

Specificité: This antibody reacts to Centractin alpha.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 97-126 amino acids from the Central region of human ACTR1A

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ACTR1A

Antigène: ACTR1A (Alpha Centractin (ACTR1A))

Autre désignation: Centractin alpha

Sujet: This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.Synonyms: ACTR1A, ARP1, Actin-RPV, CTRN1, Centrosome-associated actin homolog

ID gène: 10121

NCBI Accession: NP_005727

Pathways: M Phase