CIRBP anticorps (C-Term)
Aperçu rapide pour CIRBP anticorps (C-Term) (ABIN951531)
Antigène
Voir toutes CIRBP AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody reacts to CIRBP.
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide selected from the C-terminal region of human CIRBP
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
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Autre désignation
- CIRBP
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Sujet
- CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP
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Poids moléculaire
- 18648 Da
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ID gène
- 1153
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NCBI Accession
- NP_001271
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Antigène
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