CIRBP anticorps (C-Term)

N° du produit ABIN951531

Détail du produit anti-CIRBP anticorps

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CIRBP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CIRBP.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide selected from the C-terminal region of human CIRBP

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CIRBP

Antigène: CIRBP (Cold Inducible RNA Binding Protein (CIRBP))

Autre désignation: CIRBP (CIRBP Produits)

Synonymes: anticorps CIRP, anticorps Cirp, anticorps R74941, anticorps Xcirp, anticorps cirbp, anticorps cirbp-a, anticorps cirbp2, anticorps cirp, anticorps cirp1, anticorps cirp2, anticorps xcirp2, anticorps XCIRP, anticorps XCIRP-1, anticorps cirbp-b, anticorps cirp-1, anticorps APBP-1, anticorps zgc:136559, anticorps CIRBP, anticorps A18 hnRNP, anticorps cold inducible RNA binding protein, anticorps cold-inducible RNA-binding protein, anticorps cold inducible RNA binding protein S homeolog, anticorps cold inducible RNA binding protein L homeolog, anticorps cold inducible RNA binding protein b, anticorps CIRBP, anticorps EDI_107320, anticorps Cirbp, anticorps cirbp.S, anticorps cirbp.L, anticorps cirbp, anticorps cirbpb

Sujet: CIRBP is cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator and seems to play an essential role in cold-induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. This protein acts as a translational repressor (By similarity) and promotes assembly of stress granules (SGs), when overexpressed.Synonyms: A18HNRNP, CIRP, Cold-inducible RNA-binding protein, Glycine-rich RNA-binding protein CIRP

Poids moléculaire: 18648 Da

ID gène: 1153

NCBI Accession: NP_001271

Pathways: Ribonucleoprotein Complex Subunit Organization