Claudin 6 anticorps (Middle Region)

N° du produit ABIN951551

L’anticorps anti-Claudin 6 Polyclonal Lapin est utilisé pour la détection de Claudin 6 dans des échantillons de Humain et Souris. Il a été validé pour WB et EIA.

Aperçu rapide pour Claudin 6 anticorps (Middle Region) (ABIN951551)

Antigène: Claudin 6 (CLDN6)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Claudin 6 anticorps

Épitope: AA 133-163, Middle Region

Specificité: This antibody recognizes Human CLDN6. Other species not tested.

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 133-163 amino acids from the Central region of human CLDN6

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Claudin 6

Antigène: Claudin 6 (CLDN6)

Autre désignation: Claudin-6 / CLDN6

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.Synonyms: PRO1488, Skullin, Skullin 2, UNQ757

Poids moléculaire: 23292 Da

ID gène: 9074

NCBI Accession: NP_067018

Pathways: Hepatitis C