Factor VII anticorps

N° du produit ABIN951602

L’anticorps Souris Monoclonal anti-Factor VII a été validé pour WB et EIA. Il convient pour détecter Factor VII dans des échantillons de Humain. Il y a 1 publication disponible.

Aperçu rapide pour Factor VII anticorps (ABIN951602)

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Factor VII est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AA-3

Détail du produit anti-Factor VII anticorps

Specificité: This antibody is specific for factor VII/VIIa (AA-3).

Réactivité croisée (Details): Also reacts to: VIIa

Purification: Affinity chromatography on Protein G

Immunogène: Human Factor VII (AA-3) purified from plasma.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-Factor VII (ABIN951602)

Schut, Kirschbaum, Adelmeijer, de Groot, Lisman: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." dans: British journal of haematology, (2016) (PubMed).

Détails sur Factor VII

Antigène: Factor VII (F7) (Coagulation Factor VII (F7))

Sujet: Human blood coagulation factor VII is a 50 kD, vitamin K dependent, plasma glycoprotein synthesized in the liver and secreted into the blood as a single chain zymogen of serine protease factor VIIa. Factor VII participates in a cascade of reactions leading to the coagulation of blood and contains two Epidermal Growth Factor (EGF) domains. This antibody recognizes an epitope in the first EGF-like domain of factor VII/VIIa. Factor VII participates in the extrinsic pathway of blood coagulation in an Activated form called factor VIIa. Factor VII can be converted to VIIa by Factor IXa or thrombin.Synonyms: Proconvertin, SPCA, Serum prothrombin conversion accelerator

ID gène: 2155

NCBI Accession: NP_000122

UniProt: P08709

Pathways: Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling