Factor XI anticorps (Middle Region)

N° du produit ABIN951607

Détail du produit anti-Factor XI anticorps

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Épitope: AA 288-315, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor XI est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human Coagulation factor XI (F11) (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 288-315 amino acids from the Central region of human F11.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Factor XI

Antigène: Factor XI (F11) (Coagulation Factor XI (F11))

Abstract: F11 Produits

Synonymes: anticorps FXI, anticorps 1600027G01Rik, anticorps AI503996, anticorps Cf11, anticorps LRRGT00086, anticorps coagulation factor XI, anticorps F11, anticorps CpipJ_CPIJ000593, anticorps CpipJ_CPIJ001060, anticorps CpipJ_CPIJ002752, anticorps CpipJ_CPIJ003631, anticorps CpipJ_CPIJ004041, anticorps CpipJ_CPIJ004093

Sujet: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].Synonyms: FX1, PTA, Plasma thromboplastin antecedent

Poids moléculaire: 70109 Da

ID gène: 2160

NCBI Accession: NP_000119