Factor XI anticorps (Middle Region)
Aperçu rapide pour Factor XI anticorps (Middle Region) (ABIN951607)
Antigène
Voir toutes Factor XI (F11) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 288-315, Middle Region
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Specificité
- This antibody recognizes Human Coagulation factor XI (F11) (Center).
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 288-315 amino acids from the Central region of human F11.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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Sujet
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq].Synonyms: FX1, PTA, Plasma thromboplastin antecedent
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Poids moléculaire
- 70109 Da
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ID gène
- 2160
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NCBI Accession
- NP_000119
Antigène
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