Complement C2 anticorps (N-Term)

N° du produit ABIN951633

Cet anticorps anti-Complement C2 Polyclonal Lapin (ABIN951633) détecte spécifiquement Complement C2 dans WB. L’anticorps est réactif avec des échantillons de Humain et Hamster.

Aperçu rapide pour Complement C2 anticorps (N-Term) (ABIN951633)

Antigène: Complement C2

Reactivité: Humain, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Complement C2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Complement C2 anticorps

Épitope: AA 150-180, N-Term

Specificité: This antibody reacts to Complement C2.

Réactivité croisée (Details): Species reactivity (tested):Human and Hamster.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Complement C2

Antigène: Complement C2

Sujet: Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.Synonyms: C2, C3/C5 convertase, Complement component 2

ID gène: 717

NCBI Accession: NP_000054