Complex IV Subunit VIb (AA 58-86), (C-Term) anticorps

N° du produit ABIN951654

Détail du produit

Antigène: Complex IV Subunit VIb

Épitope: AA 58-86, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Specificité: This antibody reacts to COX6B1.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 58-86 amino acids from the C-terminal region of human COX6B1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détail du antigène

Antigène: Complex IV Subunit VIb

Sujet: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIb. Mutations in this gene are associated with severe infantile encephalomyopathy. Three pseudogenes COX6BP-1, COX6BP-2 and COX6BP-3 have been found on chromosomes 7, 17 and 22q13.1-13.2, respectively.Synonyms: COX6B, COX6B1, Cytochrome c oxidase subunit 6B1, Mitochondria Complex IV

Poids moléculaire: 10192 Da

ID gène: 1340

NCBI Accession: NP_001854