Cet anticorps anti-Coronin 1a Polyclonal Poulet (ABIN951669) détecte spécifiquement Coronin 1a dans IF et IHC (p).
L’anticorps est réactif avec des échantillons de Humain et Souris.
Synthetic peptide KLH conjugated corresponding to a sequence shared between the Mouse (NP_034028) and Human (NP_009005) gene products. After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks.
Human Coronin 1a is a 51,026 dalton protein (461 amino acids) selectively expressed in cells involved in immune surveillance throughout the body, including activated microglial cells of the CNS. It is a member of the WD40 (tryptophan-aspartate) gene family, which includes the β subunit of the trimeric G proteins as the prototype. Its function is presumably in membrane structural reorganization accompanying antigenpresentation.Synonyms: CORO1, CORO1A, Clipin-A, Coronin-like protein, Coronin-like protein p57, TACO, Tryptophan aspartate-containing coat protein