CPT1C anticorps (C-Term)

N° du produit ABIN951689

L’anticorps Lapin Polyclonal anti-CPT1C a été validé pour WB, FACS et EIA. Il convient pour détecter CPT1C dans des échantillons de Humain.

Aperçu rapide pour CPT1C anticorps (C-Term) (ABIN951689)

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CPT1C est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Détail du produit anti-CPT1C anticorps

Épitope: AA 759-790, C-Term

Specificité: This antibody reacts to CPT1C.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 759-790 amino acids from the C-terminal region of human CPT1C

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CPT1C

Antigène: CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))

Autre désignation: CPT1C / CPT1-B

Sujet: The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.Synonyms: CPT IC, Carnitine O-palmitoyltransferase 1, Carnitine palmitoyltransferase 1C, brain isoform

Poids moléculaire: 90989 Da

ID gène: 126129

NCBI Accession: NP_001129524

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process