CTPS2 anticorps (C-Term)

N° du produit ABIN951729

Détail du produit anti-CTPS2 anticorps

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Épitope: AA 449-479, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CTPS2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CTPS2.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 449-479 amino acids from the C-terminal region of human CTPS2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CTPS2

Antigène: CTPS2 (CTP Synthase II (CTPS2))

Autre désignation: CTP Synthase 2 (CTPS2 Produits)

Synonymes: anticorps A830031M15Rik, anticorps AI326475, anticorps Ctpsh, anticorps CTP synthase 2 L homeolog, anticorps CTP synthase 2, anticorps cytidine 5'-triphosphate synthase 2, anticorps ctps2.L, anticorps CTPS2, anticorps ctps2, anticorps Ctps2

Sujet: The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.Synonyms: CTP synthetase 2, CTPS2, UTP-ammonia ligase 2

Poids moléculaire: 65678 Da

ID gène: 56474

NCBI Accession: NP_001137474

Pathways: Ribonucleoside Biosynthetic Process