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Cyclin T1 anticorps (Middle Region)

CCNT1 Reactivité: Humain, Souris WB, FACS, IHC (p), EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN951765
  • Antigène Voir toutes Cyclin T1 (CCNT1) Anticorps
    Cyclin T1 (CCNT1)
    Épitope
    • 7
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 256-285, Middle Region
    Reactivité
    • 41
    • 11
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 38
    • 3
    Lapin
    Clonalité
    • 40
    • 1
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cyclin T1 est non-conjugé
    Application
    • 29
    • 17
    • 10
    • 9
    • 8
    • 6
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificité
    This antibody reacts to CCNT1.
    Réactivité croisée (Details)
    Species reactivity (tested):Human and Mouse.
    Purification
    Affinity chromatography on Protein A
    Immunogène
    KLH conjugated synthetic peptide between 256-285 amino acids from the Central region of human CCNT1
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CCNT1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS, 0.09 % (W/V) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Kapasi, Clark, Tran, Spector: "Recruitment of cdk9 to the immediate-early viral transcriptosomes during human cytomegalovirus infection requires efficient binding to cyclin T1, a threshold level of IE2 86, and active transcription." dans: Journal of virology, Vol. 83, Issue 11, pp. 5904-17, (2009) (PubMed).

  • Antigène
    Cyclin T1 (CCNT1)
    Autre désignation
    Cyclin T1 (CCNT1 Produits)
    Synonymes
    anticorps CG6292, anticorps Dmcyclin T, anticorps Dmel\\CG6292, anticorps ORE-14, anticorps P-TEFb, anticorps anon-74EFc, anticorps dT, anticorps p124, anticorps Cyclin-T1, anticorps ccnt, anticorps cyct1, anticorps CCNT, anticorps CYCT1, anticorps HIVE1, anticorps 2810478G24Rik, anticorps AI115585, anticorps CycT1, anticorps fi75b02, anticorps si:dkey-18f23.10, anticorps wu:fi75b02, anticorps Cyclin T, anticorps cyclin T1, anticorps cyclin T1 L homeolog, anticorps CycT, anticorps CCNT1, anticorps ccnt1, anticorps Ccnt1, anticorps ccnt1.L
    Sujet
    CCNT1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin tightly associates with CDK9 kinase, and was found to be a major subunit of the transcription elongation factor p-TEFb. The kinase complex containing this cyclin and the elongation factor can interact with, and act as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and was shown to be both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner were also found to be involved in the phosphorylation and regulation of the carboxy-terminal domain (CTD) of the largest RNA polymerase II subunit.Synonyms: CCNT1, CycT1, Cyclin-T, Cyclin-T1
    Poids moléculaire
    80685 Da
    ID gène
    904
    NCBI Accession
    NP_001231
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