Cytohesin 2 anticorps (N-Term)

N° du produit ABIN951803

Détail du produit anti-Cytohesin 2 anticorps

Antigène: Cytohesin 2 (CYTH2)

Épitope: AA 35-64, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cytohesin 2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Mouse Cytohesin 2 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of Human Cytohesin 2 (N-term). Genename: CYTH2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Cytohesin 2

Antigène: Cytohesin 2 (CYTH2)

Autre désignation: Cytohesin 2 (CYTH2 Produits)

Sujet: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83 % homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: ARF exchange factor, ARF nucleotide-binding site opener, ARNO, CYTH2, PH, PSCD2, PSCD2L, SEC7 and coiled-coil domain-containing protein 2

Poids moléculaire: 46546 Da

ID gène: 9266

NCBI Accession: NP_004219