L’anticorps anti-Cytohesin 2 Polyclonal Lapin est utilisé pour la détection de Cytohesin 2 dans des échantillons de Humain et Souris. Il a été validé pour WB et EIA.
CYTH2
Reactivité: Humain, Rat
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 680
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS containing 0.09 % (W/V) Sodium Azide as preservative
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Antigène
Cytohesin 2 (CYTH2)
Autre désignation
Cytohesin 2
Sujet
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The encoded protein exhibits GEP activity in vitro with ARF1, ARF3, and ARF6 and is 83 % homologous to CYTH1. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: ARF exchange factor, ARF nucleotide-binding site opener, ARNO, CYTH2, PH, PSCD2, PSCD2L, SEC7 and coiled-coil domain-containing protein 2