Desmoglein 3 anticorps (N-Term)
Aperçu rapide pour Desmoglein 3 anticorps (N-Term) (ABIN951892)
Antigène
Voir toutes Desmoglein 3 (DSG3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 7-36, N-Term
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Specificité
- This antibody recognizes Human Desmoglein-3 (N-term).
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Purification
- Affinity Chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 7-36 amino acids from the N-terminal region of Human Desmoglein-3 Genename: DSG3
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Desmoglein 3 (DSG3)
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Autre désignation
- Desmoglein-3
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Sujet
- Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.Synonyms: 130 kDa pemphigus vulgaris antigen, CDHF6, Cadherin family member 6, DSG3, PVA
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Poids moléculaire
- 107533 Da
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ID gène
- 1830
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NCBI Accession
- NP_001935
Antigène
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