Emilin1 anticorps

N° du produit ABIN952077

Cet anticorps anti-Emilin1 Monoclonal Rat (Clone C11A8) (ABIN952077) détecte spécifiquement Emilin1 dans WB, IHC (fro) et IF. L’anticorps est réactif avec des échantillons de Souris.

Aperçu rapide pour Emilin1 anticorps (ABIN952077)

Antigène: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Emilin1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: C11A8

Détail du produit anti-Emilin1 anticorps

Specificité: This antibody was selected for its ability to detect Murine Emilin-1.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Affinity Chromatography on Protein G

Immunogène: Recombinant Mouse Emilin-1

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Emilin1

Antigène: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Autre désignation: EMILIN1

Sujet: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

ID gène: 100952

NCBI Accession: NP_598679

UniProt: Q99K41