Emilin1 anticorps

N° du produit ABIN952077

Détail du produit anti-Emilin1 anticorps

Antigène: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Emilin1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Specificité: This antibody was selected for its ability to detect Murine Emilin-1.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Affinity Chromatography on Protein G

Immunogène: Recombinant Mouse Emilin-1

Clone: C11A8

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration is 0.1-1.0 mg/mL. Centrifuge vial prior to opening.

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C for one month or at -20 °C for longer. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Emilin1

Antigène: Emilin1 (EMILIN1) (Elastin Microfibril Interfacer 1 (EMILIN1))

Autre désignation: EMILIN1 (EMILIN1 Produits)

Synonymes: anticorps im:7159005, anticorps si:dkey-20n10.2, anticorps wu:fc16f07, anticorps zgc:136949, anticorps EMILIN1, anticorps 5830419M17Rik, anticorps AW229038, anticorps BB105748, anticorps EMILIN-1, anticorps gp115, anticorps EMI, anticorps EMILIN, anticorps elastin microfibril interfacer 1, anticorps elastin microfibril interfacer 1a, anticorps elastin microfibril interfacer 1b, anticorps elastin microfibril interfacer 1 L homeolog, anticorps Emilin1, anticorps emilin1a, anticorps emilin1b, anticorps EMILIN1, anticorps emilin1.L

Sujet: Emilin-1 is an extracellular matrix glycoprotein localized at sites where elastin and microfibrils are in proximity. It may be responsible for anchoring smooth muscle cells to elastic fibers. It has cell adhesive capacity. Emilin-1 may have a role in the regulation of blood vessel assembly since it inhibits TGFB signaling by binding specifically to the pro-TGFB precursor and preventing its maturation by furin convertases in the extracellular space. TGFB proteins are the main regulators of blood vessel development and maintenance.Synonyms: EMI, EMILIN-1, Elastin microfibril interface-located protein 1, Elastin microfibril interfacer 1

ID gène: 100952

NCBI Accession: NP_598679

UniProt: Q99K41