FBXO4 anticorps (Middle Region)

N° du produit ABIN952288

Cet anticorps Lapin Polyclonal détecte spécifiquement FBXO4 dans WB et EIA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour FBXO4 anticorps (Middle Region) (ABIN952288)

Antigène: FBXO4 (F-Box Protein 4 (FBXO4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FBXO4 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-FBXO4 anticorps

Épitope: AA 231-260, Middle Region

Specificité: This antibody recognizes Human FBXO4 (Center).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 231~260 amino acids from the Center region of human FBXO4

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-FBXO4 (ABIN952288)

Barbash, Zamfirova, Lin, Chen, Yang, Nakagawa, Lu, Rustgi, Diehl: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." dans: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).

Détails sur FBXO4

Antigène: FBXO4 (F-Box Protein 4 (FBXO4))

Autre désignation: FBXO4

Sujet: FBXO4 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein belongs to the Fbxs class.Synonyms: F-box only protein 4, FBX4

Poids moléculaire: 44136 Da

ID gène: 26272

NCBI Accession: NP_036308