GRPR anticorps (Middle Region)

N° du produit ABIN952465

Cet anticorps Lapin Polyclonal détecte spécifiquement GRPR dans WB, FACS et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour GRPR anticorps (Middle Region) (ABIN952465)

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRPR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GRPR anticorps

Épitope: AA 130-160, Middle Region

Specificité: This antibody recognizes Human Gastrin-releasing peptide receptor (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 130~160 amino acids from the Central region of Human Gastrin-releasing peptide receptor Genename: GRPR

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRPR

Antigène: GRPR (Gastrin-Releasing Peptide Receptor (GRPR))

Autre désignation: Gastrin-Releasing Peptide Receptor

Sujet: Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.Synonyms: GRP-R, GRP-preferring bombesin receptor, GRPR

Poids moléculaire: 43199 Da

ID gène: 2925

NCBI Accession: NP_005305