GFAP anticorps

N° du produit ABIN952496

L’anticorps Poulet Polyclonal anti-GFAP a été validé pour WB, IF et IHC (p). Il convient pour détecter GFAP dans des échantillons de Humain, Rat et Souris. Il y a 7+ publications disponibles.

Aperçu rapide pour GFAP anticorps (ABIN952496)

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Reactivité: Humain, Rat, Souris

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp GFAP est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-GFAP anticorps

Specificité: Recognizes Glial Fibrillary Acidic Protein (GFAP).

Purification: Affinity Chromatography using a peptide column.

Immunogène: Recombinant Human GFAP (expressed in bacteria). After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.0 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted in the dark at 2-8 °C.

Références pour anticorps anti-GFAP (ABIN952496)

Venables, Lapasset, Gadea, Fort, Klinck, Irimia, Vignal, Thibault, Prinos, Chabot, Abou Elela, Roux, Lemaitre, Tazi: "MBNL1 and RBFOX2 cooperate to establish a splicing programme involved in pluripotent stem cell differentiation." dans: Nature communications, Vol. 4, pp. 2480, (2014) (PubMed).

Schoppmann, Ricken, Ilhan-Mutlu, Nirtl, Streubel, Preusser, Birner: "Downregulation of CIC does not associate with overexpression of ETV1 or MAP kinase pathway activation in gastrointestinal stromal tumors." dans: Cancer investigation, Vol. 32, Issue 7, pp. 363-7, (2014) (PubMed).

Fofana, Xiao, Thumann, Turek, Zona, Tawar, Grunert, Thompson, Zeisel, Baumert: "A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission." dans: PLoS ONE, Vol. 8, Issue 5, pp. e64221, (2013) (PubMed).

Heid, Rickelt, Zimbelmann, Winter, Schumacher, Dörflinger: "Lipid droplets, perilipins and cytokeratins--unravelled liaisons in epithelium-derived cells." dans: PLoS ONE, Vol. 8, Issue 5, pp. e63061, (2013) (PubMed).

Kanemaru, Saitoh: "High-yield expression of mouse Aos1-Uba2-fusion SUMO-activating enzyme, mAU, in a baculovirus-insect cell system." dans: Bioscience, biotechnology, and biochemistry, Vol. 77, Issue 7, pp. 1575-8, (2013) (PubMed).

Su, Chao, Huang, Weng, Jeng, Lai: "Rab5 and class III phosphoinositide 3-kinase Vps34 are involved in hepatitis C virus NS4B-induced autophagy." dans: Journal of virology, Vol. 85, Issue 20, pp. 10561-71, (2011) (PubMed).

Huang, Zhou, Saberwal, Konieczna, Horvath, Katsoulidis, Platanias, Eklund: "Interferon consensus sequence binding protein (ICSBP) decreases beta-catenin activity in myeloid cells by repressing GAS2 transcription." dans: Molecular and cellular biology, Vol. 30, Issue 19, pp. 4575-94, (2010) (PubMed).

Détails sur GFAP

Antigène: GFAP (Glial Fibrillary Acidic Protein (GFAP))

Autre désignation: GFAP

Sujet: Human GFAP is a 49,749 dalton protein (432 amino acids) expressed by astrocytes of the central nervous system. GFAP is an intermediate filament protein and acts as an intra-cellular structural component of the astrocytic cytoskeleton. During embryonic and fetal life, GFAP is also expressed by radial glial cells of the CNS. Rare mutations of the GFAP gene in humans result in Alexander's disease, one of the leukodystrophies.Synonyms: Glial Fibrillary Acidic Protein

ID gène: 2670

NCBI Accession: NP_001229305