H2AFY2 anticorps (N-Term)
Aperçu rapide pour H2AFY2 anticorps (N-Term) (ABIN952667)
Antigène
Voir toutes H2AFY2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 14-43, N-Term
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Specificité
- This antibody recognizes Human and Mouse H2AFY2 / MACROH2A2 (N-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 14-43 amino acids from the N-terminal region of Human H2AFY2 / MACROH2A2
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))
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Autre désignation
- H2AFY2 / MACROH2A2
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Sujet
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.Synonyms: Core histone macro-H2A.2, Histone macroH2A2, mH2A2
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Poids moléculaire
- 40058 Da
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ID gène
- 55506
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NCBI Accession
- NP_061119
Antigène
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