HAX1 anticorps (C-Term)

N° du produit ABIN952684

Cet anticorps Lapin Polyclonal détecte spécifiquement HAX1 dans WB, EIA et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour HAX1 anticorps (C-Term) (ABIN952684)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-HAX1 anticorps

Épitope: AA 160-190, C-Term

Specificité: This antibody recognizes Human HAX1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 160-190 amino acids from the C-terminal region of Human HAX1.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet: The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

Poids moléculaire: 31621 Da

ID gène: 10456

NCBI Accession: NP_001018238

Pathways: Regulation of Actin Filament Polymerization