Hepcidin anticorps (Middle Region)

N° du produit ABIN952718

Détail du produit anti-Hepcidin anticorps

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Épitope: AA 24-54, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Hepcidin est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human Hepcidin / HAMP (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 24~54 amino acids from the Central region of Human Hepcidin / HAMP

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Hepcidin

Antigène: Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))

Autre désignation: Hepcidin / HAMP (HAMP Produits)

Synonymes: anticorps HEPC, anticorps HFE2B, anticorps LEAP1, anticorps PLTR, anticorps Hepcidin, anticorps Hamp1, anticorps Hepc, anticorps Hepc1, anticorps HAMP, anticorps hepcidin, anticorps hamp1, anticorps hep1, anticorps hepcidin antimicrobial peptide, anticorps hepcidin-like, anticorps hepcidin-1, anticorps Ham percentage, anticorps HAMP, anticorps Hamp, anticorps hamp, anticorps LOC100135935, anticorps LOC106584587

Sujet: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor

Poids moléculaire: 9408 Da

ID gène: 57817

NCBI Accession: NP_066998

Pathways: Hormone Activity, Transition Metal Ion Homeostasis