Hepcidin anticorps (Middle Region)
Aperçu rapide pour Hepcidin anticorps (Middle Region) (ABIN952718)
Antigène
Voir toutes Hepcidin (HAMP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 24-54, Middle Region
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Specificité
- This antibody recognizes Human Hepcidin / HAMP (Center).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 24~54 amino acids from the Central region of Human Hepcidin / HAMP
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Hepcidin (HAMP) (Hepcidin Antimicrobial Peptide (HAMP))
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Autre désignation
- Hepcidin / HAMP
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Sujet
- HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.Synonyms: HEPC, LEAP-1, LEAP1, Liver-expressed antimicrobial peptide, PLTR, Putative liver tumor regressor
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Poids moléculaire
- 9408 Da
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ID gène
- 57817
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NCBI Accession
- NP_066998
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Pathways
- Hormone Activity, Transition Metal Ion Homeostasis
Antigène
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