HYAL2 anticorps (Middle Region)

N° du produit ABIN952808

L’anticorps anti-HYAL2 Polyclonal Lapin est utilisé pour la détection de HYAL2 dans des échantillons de Humain. Il a été validé pour WB, IHC (p) et EIA.

Aperçu rapide pour HYAL2 anticorps (Middle Region) (ABIN952808)

Antigène: HYAL2 (Hyaluronidase-2 (HYAL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HYAL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-HYAL2 anticorps

Épitope: AA 127-157, Middle Region

Specificité: This antibody recognizes Human HYAL2 / Hyaluronidase-2 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of Human HYAL2 / Hyaluronidase-2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur HYAL2

Antigène: HYAL2 (Hyaluronidase-2 (HYAL2))

Autre désignation: HYAL2 / Hyaluronidase-2

Sujet: This gene encodes a weak acid-active hyaluronidase. The encoded protein is similar in structure to other more active hyaluronidases. Hyaluronidases degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan and fragments of hyaluronan are thought to be involved in cell proliferation, migration and differentiation. Although it was previously thought to be a lysosomal hyaluronidase that is active at a pH below 4, the encoded protein is likely a GPI-anchored cell surface protein. This hyaluronidase serves as a receptor for the oncogenic virus Jaagsiekte sheep retrovirus. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes two alternatively spliced transcript variants which differ only in the 5' UTR.Synonyms: Hyal-2, Hyaluronoglucosaminidase-2, LUCA2, Lung carcinoma protein 2

Poids moléculaire: 53860 Da

ID gène: 8692

NCBI Accession: NP_003764

Pathways: Transition Metal Ion Homeostasis, Glycosaminoglycan Metabolic Process