IDH3G anticorps (C-Term)
Aperçu rapide pour IDH3G anticorps (C-Term) (ABIN952962)
Antigène
Voir toutes IDH3G AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 364-393, C-Term
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Specificité
- This antibody recognizes Human Isocitric dehydrogenase gamma / IDH3G (C-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 364~393 amino acids from the C-terminal region of human IDH3G
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))
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Autre désignation
- Isocitric Dehydrogenase gamma / IDH3G
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Sujet
- Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia.Synonyms: NAD(+)-specific ICDH gamma, mitochondrial Isocitrate dehydrogenase [NAD] subunit gamma
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Poids moléculaire
- 42794 Da
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ID gène
- 3421
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NCBI Accession
- NP_004126
Antigène
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