MAP2 anticorps
Aperçu rapide pour MAP2 anticorps (ABIN953294)
Antigène
Voir toutes MAP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes MAP-2 (Microtubule-Associated Protein-2).
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Purification
- Affinity Chromatography using a peptide column.
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Immunogène
- Two synthetic peptides KLH conjugated corresponding to different regions of the MAP-2 gene product, but are shared between the Human (NP_002365) and Mouse (P20357) sequences. Production: After repeated injections, immune eggs were collected, the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 200 µg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter- sterilized.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody undiluted in the dark at 2-8 °C.
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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Autre désignation
- MAP-2
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Sujet
- Human MAP-2 is a 199,296 dalton protein (1827 amino acids) expressed in neurons of the PNS and CNS, where it serves as a major component of the neuronal cytoskeleton. MAP-2 contributes to structural integrity and cell shape. This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The exact function of this gene is still unknown. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development.Synonyms: MAP2, Microtubule-associated protein 2, Neuronal Marker
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ID gène
- 4133
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NCBI Accession
- NP_002365
Antigène
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