MHC Class I H-2KdDd anticorps (Biotin)

N° du produit ABIN371168

L’anticorps anti-MHC Class I H-2KdDd Monoclonal Souris est utilisé pour la détection de MHC Class I H-2KdDd dans des échantillons de Souris. Il a été validé pour FACS.

Aperçu rapide pour MHC Class I H-2KdDd anticorps (Biotin) (ABIN371168)

Antigène: MHC Class I H-2KdDd

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Biotin

Application: Flow Cytometry (FACS)

Clone: 34-1-2S

Détail du produit

Purification: Protein G Chromatography

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détail du antigène

Antigène: MHC Class I H-2KdDd

Autre désignation: MHC Class I H2 Kd/Dd

Sujet: The 'classical' MHC Class I molecules are histocompatibility antigens encoded by the H-2 gene complex and consist of heterodimers of highly polymorphic alpha chains noncovalently associated with the invariant beta 2-Microglobulin. (Ref.3,4) These antigens are expressed on most nucleated cells but expression varies on different cell types. MHC Class I molecules present endogenously synthesized peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.5) MHC Class I antigens expressed on thymic epithelial cells regulate the positive and negative selection of CD8+ T cells during T cell ontogeny. (Ref.3,6)