MPP1 anticorps (Membrane Protein, Palmitoylated 1, 55kDa) (AA 304-331)

Details for Product anti-MPP1 Antibody No. ABIN953491
Antigène
  • AAG12
  • DXS552E
  • EMP55
  • MRG1
  • PEMP
  • MGC53500
  • MGC89895
  • MPP1
  • p55
  • cb997
  • zgc:77039
  • wu:fc85f03
  • 55kDa
  • C130070C03Rik
  • membrane palmitoylated protein 1
  • membrane protein, palmitoylated 1 L homeolog
  • membrane protein, palmitoylated 1
  • membrane protein, palmitoylated
  • MPP1
  • mpp1.L
  • mpp1
  • Mpp1
Épitope
AA 304-331, Middle Region
13
9
9
7
7
4
3
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain
92
37
22
1
1
1
1
1
Hôte
Lapin
80
12
Clonalité
Polyclonal
Conjugué
Cet anticorp MPP1 est non-conjugé
5
4
4
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
68
35
24
16
13
11
3
3
2
1
1
Options
Immunogène Synthetic peptide - KLH conjugated - corresponding to the central region ( between 304-331aa) of human MPP1.
Isotype Ig Fraction
Specificité This antibody recognizes human MPP1.
Purification Purified through a Protein A column followed by peptide affinity purification
Plasmids, Primers & others Plasmids, Primers & others MPP1 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation MPP1 (MPP1 Antibody Extrait)
Sujet This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: 55 kDa erythrocyte membrane protein, DXS552E, EMP55, Membrane protein, p55, palmitoylated 1
Poids moléculaire 52296 Da
ID gène 4354
NCBI Accession NP_001159932
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium azide
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation Avoid repeated freezing and thawing.
Stock 4 °C/-20 °C
Stockage commentaire Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Images (Fournisseur)
Flow Cytometry (FACS) image for anti-Membrane Protein, Palmitoylated 1, 55kDa (MPP1) (AA 304-331), (Middle Region) antibody (ABIN953491) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative con...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Membrane Protein, Palmitoylated 1, 55kDa (MPP1) (AA 304-331), (Middle Region) antibody (ABIN953491) Immunohistochemistry analysis in human placenta tissue (Formalin-fixed, Paraffin-embe...
Western Blotting (WB) image for anti-Membrane Protein, Palmitoylated 1, 55kDa (MPP1) (AA 304-331), (Middle Region) antibody (ABIN953491) Western blot analysis in Jurkat cell line lysates (35ug/lane) using MPP1 Antibody . T...
Western Blotting (WB) image for anti-Membrane Protein, Palmitoylated 1, 55kDa (MPP1) (AA 304-331), (Middle Region) antibody (ABIN953491) Western blot analysis of MPP1 (arrow) with 293 cell lysates (2 ug/lane) either nontra...
Background publications Seo, Quinn, Khan, Zeng, Takoudis, Hanada, Bolis, Bolino, Chishti: "Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin." dans: Experimental biology and medicine (Maywood, N.J.), Vol. 234, Issue 3, pp. 255-62, 2009 (PubMed).

Seo, Jeong, Zeng, Takoudis, Quinn, Khan, Hanada, Chishti: "Alternatively spliced exon 5 of the FERM domain of protein 4.1R encodes a novel binding site for erythrocyte p55 and is critical for membrane targeting in epithelial cells." dans: Biochimica et biophysica acta, Vol. 1793, Issue 2, pp. 281-9, 2009 (PubMed).

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