MPZ anticorps

N° du produit ABIN953494

Cet anticorps Poulet Polyclonal détecte spécifiquement MPZ dans WB, IHC (p) et IF. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour MPZ anticorps (ABIN953494)

Antigène: MPZ (Myelin Protein Zero (MPZ))

Reactivité: Humain, Souris

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp MPZ est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Détail du produit anti-MPZ anticorps

Specificité: Recognizes P0 Myelin Protein.

Purification: Affinity Chromatography using a peptide column.

Immunogène: Two antipeptide antibodies were generated in Chickens against sequences shared between the Mouse (NP_032649) and Human (NP_000521) gene products. Production: After repeated injections, immune eggs were collected, and the IgY fractions were purified from the yolks. These IgY fractions were then affinity-purified using a peptide column, and the concentrations of the eluates adjusted to 0.2 mg/ml. Finally, equal volumes of both of these affinity purified anti-peptide antibodies were mixed, and the preparation was filter-sterilized.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 10 mM PBS, pH 7.2 containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted in the dark at 2-8 °C.

Détails sur MPZ

Antigène: MPZ (Myelin Protein Zero (MPZ))

Autre désignation: MPZ

Sujet: Human Myelin Protein Zero (Po) is a 28,400 dalton protein (258 amino acids) found in myelin of the PNS, but not the CNS. Expressed in myelinating Schwann cells, Po serves as a homophilic adhesion molecule, allowing adjacent laminae of the myelin sheath to undergo compaction. Po is also a marker of a subpopulation of migrating neural crest cells. Mutations of the MPZ gene product in humans is responsible for Charcot-Marie-Tooth type 1B neuropathies (HMSN1B).Synonyms: MPP, Myelin P0 protein, Myelin peripheral protein, Myelin protein zero

ID gène: 4359

NCBI Accession: NP_000521