MRGPRX2 anticorps (C-Term)

N° du produit ABIN953498

Détail du produit anti-MRGPRX2 anticorps

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Épitope: AA 286-316, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRGPRX2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes MRGPRX2 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 286-316aa) of human MRGPRX2.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MRGPRX2

Antigène: MRGPRX2 (G Protein-Coupled Receptor MRGX2 (MRGPRX2))

Autre désignation: MRGPRX2 (MRGPRX2 Produits)

Synonymes: anticorps MRGX2, anticorps G370024M05Rik, anticorps MrgB10, anticorps Mrgprb10, anticorps MrgB1, anticorps Mrgprb1, anticorps MAS related GPR family member X2, anticorps MAS-related GPR, member X2, anticorps MRGPRX2, anticorps Mrgprx2

Sujet: MRGPRX2 is the orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.Synonyms: MRGX2, Mas-related G-protein coupled receptor member X2

ID gène: 117194

NCBI Accession: NP_473371