PABPN1 anticorps (C-Term)

N° du produit ABIN953974

Cet anticorps Lapin Polyclonal détecte spécifiquement PABPN1 dans WB et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PABPN1 anticorps (C-Term) (ABIN953974)

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PABPN1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PABPN1 anticorps

Épitope: AA 269-298, C-Term

Specificité: This antibody recognizes Human PABPN1 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human PABPN1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PABPN1

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Autre désignation: PABPN1

Sujet: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails on the 3' ends of eukaryotic genes and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. An expansion of the trinucleotide (GCG) repeat from normal 6 to 8-13 at the 5' end of the coding region of this gene leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Multiple splice variants have been described but their full-length nature is not known. One splice variant includes introns 1 and 6 but no protein is formed.Synonyms: Nuclear poly(A)-binding protein 1, PAB2, PABP-2, PABP2, Poly(A)-binding protein 2, Polyadenylate-binding nuclear protein 1, Polyadenylate-binding protein 2

Poids moléculaire: 32749 Da

ID gène: 8106

NCBI Accession: NP_004634