PCDHA7 anticorps (Middle Region)
Aperçu rapide pour PCDHA7 anticorps (Middle Region) (ABIN954035)
Antigène
Voir toutes PCDHA7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 279-308, Middle Region
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Specificité
- This antibody detecs human PCDHA7 (Center).
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 279-308 aa) of human PCDHA7.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PCDHA7 (Protocadherin alpha 7 (PCDHA7))
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Autre désignation
- PCDHA7
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Sujet
- The PCDHA7 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.Synonyms: CNRS4, PCDH-alpha-7, Protocadherin alpha-7
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ID gène
- 56141
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NCBI Accession
- NP_061733
Antigène
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