PCDHGA8 anticorps (C-Term)
Aperçu rapide pour PCDHGA8 anticorps (C-Term) (ABIN954049)
Antigène
Voir toutes PCDHGA8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 788-816, C-Term
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Specificité
- This antibody recognizes Human PCDHGA8 (C-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 788-816 amino acids from the C-terminal region of Human PCDHGA8
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PCDHGA8 (Protocadherin gamma Subfamily A, 8 (PCDHGA8))
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Autre désignation
- PCDHGA8
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Sujet
- This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.Synonyms: KIAA0327, PCDH-gamma-A8, Protocadherin gamma-A8
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Poids moléculaire
- 101480 Da
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ID gène
- 9708
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NCBI Accession
- NP_054723
Antigène
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