PDZK1 anticorps (Middle Region)

N° du produit ABIN954079

Cet anticorps Lapin Polyclonal détecte spécifiquement PDZK1 dans WB, IHC (p) et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PDZK1 anticorps (Middle Region) (ABIN954079)

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDZK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-PDZK1 anticorps

Épitope: AA 195-224, Middle Region

Specificité: This antibody recognizes Human PDZK1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 195-224 amino acids from the Central region of human PDZK1

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PDZK1

Antigène: PDZK1 (PDZ Domain Containing 1 (PDZK1))

Autre désignation: PDZD1

Sujet: A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism. May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function (By similarity).Synonyms: CAP70, NHE-RF3, NHERF-3, NHERF3, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, NaPi-Cap1, PDZ domain-containing protein 1, PDZK1, Sodium-hydrogen exchanger regulatory factor 3

Poids moléculaire: 57129 Da

ID gène: 5174

NCBI Accession: NP_001188254