PKD2 anticorps (C-Term)
Aperçu rapide pour PKD2 anticorps (C-Term) (ABIN954155)
Antigène
Voir toutes PKD2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 873-903, C-Term
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Specificité
- This antibody recognizes Human and Mouse PKD2 (C-term).
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Purification
- Protein A column, followed by peptide affinity purification
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Immunogène
- KLH conjugated synthetic peptide between 873-903 amino acids from the C-terminal region of human PKD2
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))
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Autre désignation
- PKD2
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Sujet
- This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.Synonyms: Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystin-2, Polycystwin, R48321
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Poids moléculaire
- 109691 Da
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ID gène
- 5311
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NCBI Accession
- NP_000288
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Pathways
- cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Antigène
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