PKD2 anticorps (C-Term)

N° du produit ABIN954155

L’anticorps anti-PKD2 Polyclonal Lapin est utilisé pour la détection de PKD2 dans des échantillons de Humain et Souris. Il a été validé pour WB et EIA.

Aperçu rapide pour PKD2 anticorps (C-Term) (ABIN954155)

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PKD2 anticorps

Épitope: AA 873-903, C-Term

Specificité: This antibody recognizes Human and Mouse PKD2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 873-903 amino acids from the C-terminal region of human PKD2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2

Sujet: This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.Synonyms: Autosomal dominant polycystic kidney disease type II protein, Polycystic kidney disease 2 protein, Polycystin-2, Polycystwin, R48321

Poids moléculaire: 109691 Da

ID gène: 5311

NCBI Accession: NP_000288

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity