PNMT anticorps (N-Term)
Aperçu rapide pour PNMT anticorps (N-Term) (ABIN954226)
Antigène
Voir toutes PNMT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-282, N-Term
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Specificité
- The antibody recognizes human PNMT. Other species not tested.
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Purification
- Protein-G affinity chromatography
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Immunogène
- Recombinant human PNMT (1-282aa) purified from E. coli
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PNMT (Phenylethanolamine N-Methyltransferase (PNMT))
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Autre désignation
- PNMT / PENT
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Sujet
- Phenylethanolamine N-methyltransferase (PNMT) catalyzes the synthesis of epinephrine and plays an important role in regulating cardiovascular function. Expression of PNMT is regulated by hormonal and neural stimuli because its promoter contains sequences responding to cholinergic and depolarization stimuli. PNMT is the final enzyme in the catecholamine pathway, catalyzing the conversion of norepinephrine to epinephrine using as the cosubstrate and methyl donor, S-adenosylmethionine.Synonyms: Noradrenaline N-methyltransferase, PNMTase, Phenylethanolamine N-methyltransferase
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ID gène
- 5409
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NCBI Accession
- NP_002677
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UniProt
- P11086
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Pathways
- Response to Water Deprivation
Antigène
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