PROC anticorps

N° du produit ABIN954315

Cet anticorps anti-PROC est un anticorps Souris Monoclonal détectant PROC dans WB et EIA. Adapté pour Humain.

Aperçu rapide pour PROC anticorps (ABIN954315)

Antigène: PROC (Vitamin K-dependent protein C (PROC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PROC est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: CaC-11

Détail du produit anti-PROC anticorps

Specificité: This antibody is specific for Human Protein C/APC in the presence of 5-10 mM CaCl2.

Purification: Affinity chromatography on Protein G

Immunogène: Human Protein C purified from the supernatant of thrombin activated platelets.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PROC

Antigène: PROC (Vitamin K-dependent protein C (PROC))

Autre désignation: Protein C / PROC

Sujet: Protein C (PC) is a major physiological anticoagulant, and an important regulator of the blood coagulation system. PC is a vitamin K dependent serine protease enzyme that is activated by thrombin. The anticoagulant PC is converted to activated protein C (APC) by the thrombomodulin (TM) - thrombin complex on the phospholipid surface of endothelial cells, monocytes and platelets. APC degrades coagulation Factors Va and VIIIa rendering these factors inactive. APC provides physiologic antithrombotic activity and exhibits both anti-inflammatory and anti-apoptotic activity. Treatment with APC has been shown to improve the clinical outcome of patients with sepsis.Synonyms: Anticoagulant protein C, Autoprothrombin IIA, Blood coagulation factor XIV, Inactivator of coagulation factors Va and VIIIa, PROC1, Vitamin K-dependent protein C

ID gène: 5624

NCBI Accession: NP_000303

UniProt: P04070