PC anticorps (N-Term)
Aperçu rapide pour PC anticorps (N-Term) (ABIN954396)
Antigène
Voir toutes PC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 52-82, N-Term
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Specificité
- This antibody reacts to PC.
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Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PC (Pyruvate Carboxylase (PC))
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Autre désignation
- Pyruvic Carboxylase (PC)
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Sujet
- This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].Synonyms: PCB, Pyruvate carboxylase mitochondrial
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ID gène
- 5091
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NCBI Accession
- NP_000911
Antigène
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