RBM5 anticorps (N-Term)

N° du produit ABIN954485

L’anticorps Lapin Polyclonal anti-RBM5 a été validé pour WB et EIA. Il convient pour détecter RBM5 dans des échantillons de Humain.

Aperçu rapide pour RBM5 anticorps (N-Term) (ABIN954485)

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RBM5 anticorps

Épitope: AA 17-46, N-Term

Specificité: This antibody recognizes Human RBM5 (N-term).

Purification: Affinity Chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of Human RBM5. Genename: RBM5

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RBM5

Antigène: RBM5 (RNA Binding Motif Protein 5 (RBM5))

Autre désignation: RBM5 / LUCA15

Sujet: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosisSynonyms: NY-REN-9, Putative tumor suppressor LUCA15, RNA-binding motif protein 5, RNA-binding protein 5, Renal carcinoma antigen NY-REN-9

Poids moléculaire: 92154 Da

ID gène: 10181

NCBI Accession: NP_005769

Pathways: Ribonucleoprotein Complex Subunit Organization