RUNX3 anticorps (Middle Region)

N° du produit ABIN954644

L’anticorps anti-RUNX3 Polyclonal Lapin est utilisé pour la détection de RUNX3 dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour RUNX3 anticorps (Middle Region) (ABIN954644)

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-RUNX3 anticorps

Épitope: AA 167-197, Middle Region

Purification: Protein A column followed by peptide Affinity purification

Immunogène: KLH conjugated synthetic peptide between 167-197 amino acids from the Central region of Human RUNX3 Genename: RUNX3

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur RUNX3

Antigène: RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

Autre désignation: RUNX3

Sujet: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.Synonyms: AML2, Acute myeloid leukemia 2 protein, CBF-alpha-3, CBFA3, Core-binding factor subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2-alpha C, PEBP2A3, Polyomavirus enhancer-binding protein 2 alpha C subunit, Runt-related transcription factor 3, SL3-3 enhancer factor 1 alpha C subunit, SL3/AKV core-binding factor alpha C subunit

ID gène: 864

NCBI Accession: NP_001026850