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SPR anticorps (C-Term)

Cet anticorps anti-SPR est un anticorps Lapin Polyclonal détectant SPR dans WB et EIA. Adapté pour Humain et Souris.
N° du produit ABIN954723

Aperçu rapide pour SPR anticorps (C-Term) (ABIN954723)

Antigène

Voir toutes SPR Anticorps
SPR (Sepiapterin Reductase (SPR))

Reactivité

  • 54
  • 27
  • 18
  • 3
  • 1
  • 1
  • 1
Humain, Souris

Hôte

  • 43
  • 12
Lapin

Clonalité

  • 46
  • 9
Polyclonal

Conjugué

  • 28
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp SPR est non-conjugé

Application

  • 48
  • 18
  • 13
  • 13
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • 3
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 232-261, C-Term

    Specificité

    This antibody recognizes Sepiapterin reductase / SPRat N-term.

    Réactivité croisée (Details)

    Species reactivity (tested):Human, Mouse

    Purification

    Purified through a Protein A column followed by peptide affinity purification

    Immunogène

    Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 232-261aa) of human Sepiapterin reductase / SPR.

    Isotype

    Ig Fraction
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) Sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    SPR (Sepiapterin Reductase (SPR))

    Autre désignation

    Sepiapterin Reductase / SPR

    Sujet

    The SPR gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency. A pseudogene has been identified on chromosome 1.Synonyms: EC 1.1.1.153, SDR38C1, short chain dehydrogenase/reductase family 38C member 1

    ID gène

    6697

    NCBI Accession

    NP_003115

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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