SPR anticorps (C-Term)
Aperçu rapide pour SPR anticorps (C-Term) (ABIN954723)
Antigène
Voir toutes SPR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 232-261, C-Term
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Specificité
- This antibody recognizes Sepiapterin reductase / SPRat N-term.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse
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Purification
- Purified through a Protein A column followed by peptide affinity purification
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 232-261aa) of human Sepiapterin reductase / SPR.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SPR (Sepiapterin Reductase (SPR))
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Autre désignation
- Sepiapterin Reductase / SPR
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Sujet
- The SPR gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiapterin reductase deficiency. A pseudogene has been identified on chromosome 1.Synonyms: EC 1.1.1.153, SDR38C1, short chain dehydrogenase/reductase family 38C member 1
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ID gène
- 6697
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NCBI Accession
- NP_003115
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
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